127 THE TYPE III COLLAGEN TURNOVER AND NITROSYLATION IN A RAT MODEL OF COLLAGEN INDUCED ARTHRITIS (CIA). APPLYING THREE NOVEL ELISA'S MEASURING TYPE III COLLAGEN NEOEPITOPES
نویسندگان
چکیده
منابع مشابه
Immunohistochemical study of type III collagen expression during pre and post-natal rat skin morphogenesis
Objective(s):Skin extracellular matrix, which contains type I and type III collagens, is involved in skin development. The aim of this study was to investigate type III collagen distribution pattern as well as its changes during pre and post-natal skin morphogenesis in rats. Materials and Methods: Ventral skins of Wistar rat embryos at different stages from 10 to 20 gestational day (E10-E20) a...
متن کاملA new platelet receptor specific to type III collagen. Type III collagen-binding protein.
Platelet interaction with type III collagen is mediated by several platelet receptors that recognize specific sequences in collagen. We previously described an octapeptide KP*GEP*GPK within the alpha(1)III-CB4 fragment that binds to platelets and specifically inhibits platelet aggregation induced by type III collagen. In this study, we demonstrated that the octapeptide prevented platelet contac...
متن کاملimmunohistochemical study of type iii collagen expression during pre and post-natal rat skin morphogenesis
objective(s):skin extracellular matrix, which contains type i and type iii collagens, is involved in skin development. the aim of this study was to investigate type iii collagen distribution pattern as well as its changes during pre and post-natal skin morphogenesis in rats. materials and methods: ventral skins of wistar rat embryos at different stages from 10 to 20 gestational day (e10-e20) an...
متن کاملCollagen type I, collagen type III, and versican in vocal fold lamina propria.
OBJECTIVE To analyze the distributions of collagen type I, collagen type III, and versican in the lamina propria of the human vocal fold. DESIGN Cross-sectional analysis of cadaveric vocal folds of adult human larynges. SETTING Academic tertiary referral center. SUBJECTS Larynges harvested at autopsy from 10 adult men and 10 adult women. MAIN OUTCOME MEASURES Immunohistochemical reactio...
متن کاملType Ii Collagen - Induced Arthritis in Mice
The induction of immunological reactivity to type II collagen, a major component of cartilage, has recently been used to establish an experimental model of arthritis in the rat (1). Trentham and colleagues (1) have shown that the intradermal injection of collagen in Freund's complete or incomplete adjuvant elicits an arthritogenic reaction, specifically with native type II collagen. Arthritis o...
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ژورنال
عنوان ژورنال: Osteoarthritis and Cartilage
سال: 2011
ISSN: 1063-4584
DOI: 10.1016/s1063-4584(11)60154-4